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UN health agency announces list of bacteria for which new antibiotics are urgently needed

27 February 2017 – The United Nations health agency today published its first-ever catalogue of antibiotic-resistant bacteria that pose the greatest threat to human health.

The list of priority pathogens consisting of 12 families of bacteria was drawn up to guide and promote research and development (R&D) of new antibiotics, as part of the World Health Organization (WHO)’s efforts to address growing global resistance to antimicrobial medicines.

&#8220This list is a new tool to ensure R&D responds to urgent public health needs,&#8221 said Marie-Paule Kieny, WHO’s Assistant Director-General for Health Systems and Innovation in a news release.

&#8220Antibiotic resistance is growing, and we are fast running out of treatment options. If we leave it to market forces alone, the new antibiotics we most urgently need are not going to be developed in time,&#8221 she warned.

The list highlights in particular the threat of ‘gram-negative’ bacteria that are resistant to multiple antibiotics. These bacteria have built-in abilities to find new ways to resist treatment and can pass along genetic material that allows other bacteria to become drug-resistant as well.

The WHO list is divided into three categories according to the urgency of need for new antibiotics: critical, high and medium priority.

Priority 1: CRITICAL
  • Acinetobacter baumannii, carbapenem-resistant
  • Pseudomonas aeruginosa, carbapenem-resistant
  • Enterobacteriaceae, carbapenem-resistant, ESBL-producing

The most critical group of all includes multidrug resistant bacteria that pose a particular threat in hospitals, nursing homes, and among patients whose care requires devices such as ventilators and blood catheters. They include Acinetobacter, Pseudomonas and various Enterobacteriaceae, including Klebsiella, E. coli, Serratia, and Proteus. They can cause severe and often deadly infections such as bloodstream infections and pneumonia.

These bacteria have become resistant to a large number of antibiotics, including carbapenems and third generation cephalosporins &#8211 the best available antibiotics for treating multi-drug resistant bacteria.

G20 health experts will meet this week in Berlin. The list is intended to spur governments to put in place policies that incentivize basic science and advanced R&D by both publicly funded agencies and the private sector investing in new antibiotic discovery.

While more R&D is vital, alone, it cannot solve the problem. To address resistance, there must also be better prevention of infections and appropriate use of existing antibiotics in humans and animals, as well as rational use of any new antibiotics that are developed in future.

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Western Sahara: UN chief Guterres urges Morocco and Polisario Front to de-escalate tensions in buffer strip

25 February 2017 – Deeply concerned about increased tensions in the vicinity of Guerguerat in the buffer strip in southern Western Sahara between the Moroccan berm and the Mauritanian border, United Nations Secretary-General António Guterres today called on Morocco and Frente Polisario to &#8220take all necessary steps&#8221 to avoid escalation.

According to a statement issued by UN Spokesman Stéphane Dujarric, armed elements of both Morocco and Frente Polisario (Polisario Front) remain in close proximity to each other, a position they have been in since August 2016, monitored during daylight hours by the UN Mission for the Referendum in Western Sahara (MINURSO).

&#8220The Secretary-General calls on both of the parties to exercise maximum restraint and take all necessary steps to avoid escalating tensions, be that through the actions of military or civilian actors,&#8221 the statement said, adding that Mr. Guterres also underlined that regular commercial traffic should not be obstructed and that no action should be taken, which may constitute a change to the status quo of the buffer strip.

Strongly urging the parties to unconditionally withdraw all armed elements from the buffer strip as soon as possible, to create an environment conducive to a resumption of the dialogue in the context of the political process led by the UN, the Spokesman said Mr. Guterres further called on the parties to adhere to their obligations under the ceasefire agreement and to respect both the letter and the spirit of it.

Western Sahara is located on the north-west coast of Africa bordered by Morocco, Mauritania and Algeria. The colonial administration of Western Sahara by Spain ended in 1976. Fighting later broke out between Morocco and the Polisario Front. A ceasefire was signed in September 1991. MINURSO was deployed that year to monitor the ceasefire between the Government of Morocco and the Polisario Front and organizing, if the parties agree, a referendum on self-determination in Western Sahara.

A revised settlement plan was proposed by the United Nations after seven years of diplomatic consultations was rejected by one of the parties in 2004. In approving the current phase of direct negotiations in 2007, the UN Security Council called for &#8220a just, lasting and mutually acceptable political settlement which will provide for the self-determination of the people of Western Sahara.&#8221

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UN Security Council calls for immediate investigation into recent violence in DR Congo’s Kasai region

25 February 2017 – The United Nations Security Council has strongly condemned the recent spate of violence in the south-central Kasai region of the Democratic Republic of the Congo (DRC), calling on the Government to &#8220immediately dispatch a credible and impartial investigation.&#8221

In a press statement issued in New York yesterday evening, the Council expressed grave concern at the recent reports of serious violations of international humanitarian law committed by local militia in that region, including unlawful recruitment and use of child soldiers, and of killings of civilians by members of Congolese security forces, known as FARDC, &#8220all of which might constitute war crimes under international law.&#8221

Recalling that the DRC Government bears the primary responsibility to protect civilians within its territory, the Security Council urged the authorities to &#8220constantly exercise maximum restraint and proportionate lawful use of force in its efforts to restore order.&#8221

The Council also called on the Government to immediately dispatch an investigation and to bring to justice and hold accountable all those responsible. Welcoming the Government’s announcement in this regard, the Council encouraged the UN Stabilization Mission in the country, known by its French acronym MONUSCO, &#8220to provide support to the Congolese authorities, if requested, in the conduct of this investigation, developments in which they will follow very closely.&#8221

MONUSCO was further urged to monitor and report on violations and abuses of international human rights law and violations of international humanitarian law and to update its contingency plans in this regard. In the longer-term, the Security Council encouraged the DRC Government to continue its efforts for the extension of State authority throughout the vast central African nation, ensuring credible governance with capable institutions, especially in the security sector, to prevent and deter violence.

RELATED: UN mission in DR Congo strongly condemns persistent violence in Kasai Provinces

As for the political situation in the country, the Security Council reaffirmed its strong support for the 31 December 2016 political agreement, &#8220and its pursuit of peaceful, credible, free, fair and inclusive elections by December 2017, leading to a democratic transfer of power.&#8221

In this context, the 15-nation body said it is &#8220increasingly concerned&#8221 at the continuing lack of progress in the dialogue among the political stakeholders in DRC related to implementation modalities of the agreement. The Council expressed concern that, two months after the signing of the agreement, the appointment of a Prime Minister presented by the Rassemblement coalition, as well as the installation of a new transitional government and of the Comité National de Suivi de l’Accord (CNSA) have yet to take place.

As such, the Council stressed the need to maintain the political goodwill that led to the signing of the agreement in order to avoid further insecurity in the DRC. Further, the Council called on all stakeholders in the DRC, including President Joseph Kabila, the presidential majority and the opposition, to redouble, in good faith, their efforts towards a speedy conclusion of the ongoing talks on the &#8220arrangements particuliers&#8221 of the agreement, in order to urgently nominate a Prime Minister presented by the Rassemblement.

The Security Council reaffirmed the need for all parties to support and participate constructively in the mediation led by the Conférence épiscopale nationale du Congo (CENCO), and recalled that full and timely implementation of the 31 December agreement, in accordance with the Congolese Constitution and in line with Council resolution 2277 (2016), is critical in upholding the legitimacy of the transitional institutions until elections.

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UNESCO meeting lays groundwork for reviving, protecting Iraq’s cultural heritage

24 February 2017 – As details on the destruction of and damage to Iraq’s rich and diverse cultural heritage emerge, the United Nations cultural agency has appealed to the international community to help protect and revive the country’s archaeological, religious and cultural sites for future generations.

“This is a turning point for the Iraqi people and for the world’s understanding of the role of heritage for societies in conflict situations,” said the Director-General of the UN Educational, Scientific and Cultural Organization (UNESCO), Irina Bokova.

Speaking at the end of a two-day meeting of the International Coordination Conference on the Safeguarding of Cultural Heritage in Liberated Areas of Iraq, Ms. Bokova added: “UNESCO is already mobilizing on the ground to support Iraq in protecting heritage and objects most at risk, and to fence off and guard sites.”

The meeting also prepared the groundwork for emergency, medium and long term action plans to preserve the country’s millennial archaeological sites, museums, religious heritage, and historic cities.

It also agreed to appoint a joint UNESCO-Iraqi Steering Committee to coordinate and advocate the many national and international initiatives to rehabilitate the cultural heritage of Iraq.

However, according to UNESCO the damage already done has been much fear than what was anticipated and the rehabilitation process is likely to require decades of work.

Noting the importance of action to safeguard Iraq’s heritage, the country’s Minister of Culture Fryad Rawandouzi highlighted: “As we reclaim our country […] We need help from UNESCO, the UN and others to rehabilitate museums, cities and sites […] We need a plan with a timeline, as well as technical and financial support.”

At the same time, there are fears that antiquities taken away from heritage sites may have been sold on the Internet and the black market and the money used finance activities of the terrorist group Islamic State in Iraq and the Levant (ISIL/Da’esh).

“We must stop the trade in Iraqi antiquities, adhere to Security Council Resolution 2199, and dry up [ISIL]’s money flow,” underscored Mohammad Iqbal Omar, the Iraqi Minister of Education.

Adopted in 2015, UN Security Council resolution 2199, among other provisions, banned all trade in looted antiquities from Iraq and Syria. It also encouraged steps to ensure such items are returned to their homelands, and called on UNESCO, Interpol, and other international organizations to assist in such efforts.

“Da’esh tried, but will never erase our culture, identity, diversity, history and the pillars of civilization. I call on the world to help us,” said added the Minister of Education.

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Secretary-General asks Member States to express intention on financing UN plan to tackle cholera in Haiti

24 February 2017 – United Nations Secretary-General António Guterres has asked Member States to inform him by 6 March if they intend to make voluntary financial contributions to the implementation of the new UN plan to counter cholera in Haiti, his spokesman said today.

“Earlier this week the Secretary-General sent a letter to all Member States” in that regard, Stéphane Dujarric told reporters at the regular daily briefing at UN Headquarters in New York.

“As you are aware, under the new approach, the UN is intensifying support to the Haitian government in building sound water, sanitation and health systems – the best long-term defence against cholera and other water-borne diseases – and also developing a support package to provide material assistance and support to Haitians most directly affected by cholera,” the Spokesman said.

In his letter, the Secretary-General recalled that the UN bears a moral responsibility for ensuring that the new approach – launched in a report to UN Member States on 1 December 2016 – is implemented, Mr. Dujarric added.

RELATED: UN outlines new plan to fight cholera epidemic and help communities

Costing around $400 million over the next two years, the proposed UN package under the new approach will centre on two different elements, known as ‘Track One’ and ‘Track Two.’
Track 1 – reducing incidence of cholera

The former consists of a greatly intensified and better-resourced effort to respond to and reduce the incidence of cholera, through addressing Haiti’s short- and longer-term issues of water, sanitation and health systems and improved access to care and treatment.

This is expected to involve intensifying efforts to mobilize adequate funding for an increased number of rapid response teams; strengthened epidemiological surveillance; the rapid detection, reporting and treatment of cases; the combined use of cholera vaccinations with targeted water and sanitation interventions; more focused geographical targeting; improved communication and behavioural change strategies; and strengthened support to longer-term water and sanitation services.

Track 2 – a community approach

The second track of the UN response is the development of a package of material assistance and support to those Haitians most directly affected by cholera, centred on the victims and their families and communities. It is expected that it will also involve affected individuals and communities in the development of the package.

Haiti has been dealing with a cholera outbreak since October 2010, some nine months after it suffered a devastating earthquake. The outbreak has affected an estimated 788,000 people and claimed the lives of more than 9,000. Concerted national and international efforts, backed by the United Nations, have resulted in a 90 per cent reduction in the number of suspected cases.

While the number of those affected remains high, and recent outbreaks – partly heightened by the impact of Hurricane Matthew – show the continued vulnerability of the population to the disease, UN officials have said the challenge is not insurmountable.

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