International Development Secretary Penny Mordaunt in Djibouti with aid destined for Yemen. Picture: Benet Coulber/DFID

In an alert issued last year, healthcare professionals were asked to speak to parents and carers about carefully inspecting Buccolam pre-filled plastic syringes before giving the medicine.

Buccolam is an epilepsy medicine, which is available as pre-filled oral syringes. A defect with some syringes has been reported. In a small number of cases, the translucent (white) tip-cap can sometimes remain attached to the syringe after the red cap has been taken off, this is a choking hazard.

Buccolam remains safe to use if the patient/carer instructions are followed. Carefully check the syringe before giving the medicine and remove the translucent tip-cap manually if it is still on the syringe after the red cap has been pulled off. A diagram explaining this can be found in the alert.

If you think the tip-cap is in the patient’s mouth, do not attempt to remove it. Instead, turn the patient onto their side (recovery position) and make sure they spit it out when they stop fitting.

This is not a new issue, MHRA previously issued this alert in December 2017. However, we are now aware of a few rare reports in Europe of a child breathing in or swallowing the tip-cap and the EMA have added guidance on their website.

We want to make sure parents and carers of children who are using Buccolam are aware of the practical steps to take should they need to dispense this medicine. Pharmacists who prescribe and dispense Buccolam have also been asked to share this information with parents and caregivers.

The manufacturer is working to resolve this issue for new syringes.

If patients, parents, or carers have any questions or want to report any side effects, they should talk to a doctor, pharmacist, or nurse. They should also tell them about any occasions in which the translucent tip-cap remained attached to the syringe.

Suspected side effects can also be reported directly to MHRA via the Yellow Card Scheme.

Ms Tina Redshaw has been appointed Her Majesty’s Ambassador to the Kingdom of Cambodia.

Earlier this month, the Competition and Markets Authority (CMA) found that the proposed merger of the soft drink manufacturers could lead to higher prices for some supermarkets and leading household brands.

The CMA’s initial investigation into the £935 million ($1.25 billion) merger did not find any competition concerns for the majority of the companies’ products.

However, both companies supply juice drinks using a particular aseptic production process, which allows them to be sold preservative-free and without refrigeration. As only one other competitor in the UK currently supplies third parties with juice drinks using this production process the CMA is concerned that, after the merger, the combined business might be able to increase prices or lower quality standards.

Refresco has now offered to address the CMA’s concerns by selling the only UK-based Cott facility to use this production process. The factory, located in Nelson, Lancashire, would be sold to a purchaser approved by the CMA.

The CMA has accepted this offer in principle and now has until 14 March 2018 to decide whether to accept Refresco’s proposed undertakings or refer the merger for an in depth investigation.

All information relating to the merger is available on the case page.

Today (Wednesday 17 January) the Prime Minister will set out how government is tackling loneliness and combating social isolation.

She will announce that the government is accepting a series of recommendations from the Jo Cox Commission on Loneliness.

The Prime Minister will host a reception at Downing Street to celebrate Jo Cox’s legacy, and the important work of her family, Foundation and the Commission in highlighting how many people are experiencing loneliness.

Research shows:

• more than 9 million people always or often feel lonely
• around 200,000 older people have not had a conversation with a friend or relative in more than a month
• up to 85% of young disabled adults – 18-34 year olds – feel lonely

Ahead of the reception, the Prime Minister paid tribute to Jo Cox, her family and to those working for the Foundation and Commission for highlighting the issue.

The Prime Minister said:

For far too many people, loneliness is the sad reality of modern life.

I want to confront this challenge for our society and for all of us to take action to address the loneliness endured by the elderly, by carers, by those who have lost loved ones – people who have no one to talk to or share their thoughts and experiences with.

Jo Cox recognised the scale of loneliness across the country and dedicated herself to doing all she could to help those affected.

So I am pleased that government can build on her legacy with a ministerial lead for loneliness who will work with the Commission, businesses and charities to shine a light on the issue and pull together all strands of government to create the first ever strategy.

We should all do everything we can to see that, in Jo’s memory, we bring an end to the acceptance of loneliness for good.

The Prime Minister has today implemented the first of the Jo Cox Commission’s recommendations – appointing a ministerial lead on loneliness. The Minister for Sport and Civil Society Tracey Crouch will lead a cross-government group which will take responsibility for driving action on loneliness across all parts of government and keeping it firmly on the agenda.

In addition, work has also begun on:

• developing a cross-government strategy on loneliness in England to be published later this year. This will bring together government, local government, public services, the voluntary and community sector and businesses to identify opportunities to tackle loneliness, and build more integrated and resilient communities
• developing the evidence-base around the impact of different initiatives in tackling loneliness, across all ages and within all communities, led by the government’s What Works centres
• establishing appropriate indicators of loneliness across all ages with the Office for National Statistics so these figures can be included in major research studies
• a dedicated fund which will see government working with charitable trusts, foundations, and others to:
  • stimulate innovative solutions to loneliness across all ages, backgrounds and communities
  • provide seed funding for communities to come together to develop activities which enable people to connect
  • scale-up and spread existing work offering practical and emotional support to help lonely individuals reconnect with their communities

A number of government initiatives are already in place to help reduce loneliness, including improved mental health support, and the pocket parks programme which has transformed unused spaces into new green areas, giving lonely people the chance to join volunteering groups and interact with neighbours.

New ministerial lead for loneliness, Minister for Sport and Civil Society Tracey Crouch said:

I am privileged to be taking forward the remarkable work done by Jo Cox, the Foundation and the Commission. I am sure that with the support of volunteers, campaigners, businesses and my fellow MPs from all sides of the House, we can make significant progress in defeating loneliness.

This is an issue that Jo cared passionately about and we will honour her memory by tackling it, helping the millions of people across the UK who suffer from loneliness.

Loneliness can be triggered by a life event, such as a bereavement or becoming a parent, with certain groups, such as young people and carers, particularly at risk.

The Jo Cox Commission on Loneliness, chaired by Rachel Reeves MP and Seema Kennedy MP, has spent the last year considering what the government and others can do to help. They have been working with 13 charities including Age UK and Action for Children to develop ideas for change.

Rachel Reeves MP and Seema Kennedy MP, co-Chairs of the Commission said:

We are really pleased to see that the government is taking the issue of loneliness very seriously with its prompt response to our report. Jo Cox said that “young or old, loneliness doesn’t discriminate.

Throughout 2017 we have heard from new parents, children, disabled people, carers, refugees and older people about their experience of loneliness.

We very much welcome that government has accepted the Commission’s recommendations including the appointment of a new ministerial lead who will have the responsibility for creating a national strategy to tackle loneliness. We look forward to working with Minister Tracey Crouch, businesses, community groups and the public to create a world less lonely.

Mark Robinson, Chief Officer of Age UK Barnet said:

Loneliness can kill. It’s proven to be worse for health than smoking 15 cigarettes a day, but it can be overcome and needn’t be a factor in older people’s lives.

Age UK provide a wide variety of services and we welcome the work that the government is doing to support lonely people in communities throughout the country.

Phil Burton, a former Royal Artillery Lance Bombardier, will attend the reception to receive a Point of Light Award from the Prime Minister for his work to tackle loneliness. He founded the Veterans’ Café in Leyland which brings former members of the armed forces together, to talk, share experiences and access support from charities and the NHS. He said:

When I first started the venture with the Veterans’ Café, I never thought it would grow into something this big. I originally wanted to set this up for the veterans, so they had a place to meet, and talk to like-minded people with the same day to day issues. This has now brought the veteran community together, and is allowing veterans of all ages to get the help where needed. This would never have been possible without the help of South Ribble Council, and the veterans that support the café on a fortnightly basis.